Schizophrenia is a heritable brain illness with unknown pathogenic mechanisms. Schizophrenia’s strongest genetic association at a population level involves variation in the major histocompatibility complex (MHC) locus, but the genes and molecular mechanisms accounting for this have been challenging to identify. Here we show that
Awareness of the role of food supplements for various medical problems has been increasing in recent years. Niacin (Vitamin B3) has been proven to raise HDL and lower triglyceride levels. Niacin is a precursor to several neurotransmitters in the brain, which may have an impact on
NEW YORK (Reuters Health) – An abnormal response to niacin may help doctors differentiate between schizophrenia and bipolar disorder, new research suggests. “In our study of niacin response characteristics among 216 volunteers – the largest study of its kind – we demonstrated that the presence
Nicotinic acid (NA), often called niacin, a form of vitamin B3, is a water-soluble nutrient found in animal and vegetarian foods. Vitamin B3 for healthy people is considered to be needed in doses of less than 20 mg daily. In higher doses, NA has been
Eight young males were subjected to a single blind cross-over test to see the effects of vitamin B12 (methylcobalamin; VB12) on the phase-response of the circadian melatonin rhythm to a single bright light exposure. VB12 (0.5 mg/day) or vehicle was injected intravenously at 1230 h
This preliminary study investigates effects of methyl- and cyanocobalamin on circadian rhythms, well-being, alertness, and concentration in healthy subjects. Six women (mean age 35 years) and 14 men (mean age 37 years) were randomly assigned to treatment for 14 days with 3 mg cyano-(CB12) or