Forty-five hospitalised patients with DSM-III-R diagnosis of mania, were found to have a mean red-cell folate level of 193 nmol/l, as compared to 896 nmol/l in the control group (P < 0.00001). Assessment of serum folate in both groups showed no significant differences in the
A double-blind trial was carried out to investigate the effect on affective morbidity of a daily supplement of 200 micrograms folic acid or a matched placebo in a group of 75 patients on lithium therapy. During the trial the patients with the highest plasma folate
Both low folate and low vitamin B12 status have been found in studies of depressive patients, and an association between depression and low levels of the two vitamins is found in studies of the general population. Low plasma or serum folate has also been found
A sensational discovery has been made by experts as scientists have found that the human brain is home to structures and shapes that have up to 11 dimensions. Neuroscientists welcome the discovery saying: “We found a world that we had never imagined.” Mathematical methods of algebraic topology have
Side Effects & Safety. Citicoline is POSSIBLY SAFE when taken by mouth short-term (up to 90 days). The safety of long-term use is not known. Most people who take citicoline don’t experience problematic side effects. But some people can have side effects such as trouble sleeping (insomnia),
Over the last decade, there has been a growing appreciation of the importance of identifying and treating cognitive impairment associated with bipolar disorder, since it persists in remission periods. Evidence indicates that neurocognitive dysfunction may significantly influence patients’ psychosocial outcomes. An ever-increasing body of research
Oxidative stress has been implicated in the pathophysiology of many neuropsychiatric disorders such as schizophrenia, bipolar disorder, major depression etc. Both genetic and nongenetic factors have been found to cause increased cellular levels of reactive oxygen species beyond the capacity of antioxidant defense mechanism in
Coenzyme Q10 (CoQ10) is a vital component of cellular energy metabolism; placed within the electron transport chain of the mitochondria to facilitate ATP production (ATP being cellular energy currency, and the ultimate product of fatty acids and glucose being ‘used’ for energy). CoQ10 is named
Our most commonly held formula for success is broken. Conventional wisdom holds that if we work hard we will be more successful, and if we are more successful, then we’ll be happy. If we can just find that great job, win that next promotion, lose
A pessimist sees the difficulty in every opportunity; an optimist sees the opportunity in every difficulty.” ~Winston Churchill I am constantly striving to see the positive in every aspect of my life. But it’s not always easy. My dog is currently suffering from a disease